Sphera Funds Management Ltd 13F annual report

Sphera Funds Management Ltd is an investment fund managing more than $613 billion ran by Oshrat Levi. There are currently 109 companies in Levi’s portfolio. The largest investments include BridgeBio Pharma Inc and Sanofi, together worth $44.9 billion.

Limited to 30 biggest holdings

$613 billion Assets Under Management (AUM)

As of 7th August 2024, Sphera Funds Management Ltd’s top holding is 910,070 shares of BridgeBio Pharma Inc currently worth over $23.1 billion and making up 3.8% of the portfolio value. Relative to the number of outstanding shares of BridgeBio Pharma Inc, Sphera Funds Management Ltd owns more than approximately 0.1% of the company. In addition, the fund holds 449,515 shares of Sanofi worth $21.8 billion, whose value grew 15.8% in the past six months. The third-largest holding is Cytokinetics Inc worth $20.9 billion and the next is Amazon.com worth $19.6 billion, with 101,432 shares owned.

Currently, Sphera Funds Management Ltd's portfolio is worth at least $613 billion. The total portfolio value may be much higher due to cash assets that are not publicly disclosed such as fixed income, real estate, or cash equivalents.

Careers at Sphera Funds Management Ltd

The Sphera Funds Management Ltd office and employees reside in Tel Aviv, Israel. According to the last 13-F report filed with the SEC, Oshrat Levi serves as the Chief Financial Officer at Sphera Funds Management Ltd.

Recent trades

In the most recent 13F filing, Sphera Funds Management Ltd revealed that it had opened a new position in Skye Bioscience Inc and bought 1,298,312 shares worth $10.4 billion.

The investment fund also strengthened its position in BridgeBio Pharma Inc by buying 324,114 additional shares. This makes their stake in BridgeBio Pharma Inc total 910,070 shares worth $23.1 billion. BridgeBio Pharma Inc dropped 24.2% in the past year.

On the other hand, there are companies that Sphera Funds Management Ltd is getting rid of from its portfolio. Sphera Funds Management Ltd closed its position in Perspective Therapeutics Inc on 14th August 2024. It sold the previously owned 12,443,621 shares for $14.8 billion. Oshrat Levi also disclosed a decreased stake in Sanofi by 0.1%. This leaves the value of the investment at $21.8 billion and 449,515 shares.

One of the average hedge funds

The two most similar investment funds to Sphera Funds Management Ltd are Cornercap Investment Counsel Inc and Inscription Capital. They manage $614 billion and $613 billion respectively.


Oshrat Levi investment strategy

Sphera Funds Management Ltd’s portfolio is diversified across 6 sectors. Currently, their heaviest sector is Health Care — making up 42.3% of the total portfolio value. The fund focuses on investments in the United States as 48.6% of the portfolio companies are based in the United States.

The majority of the companies in the fund’s portfolio are large-cap stocks. Stocks with a size of more than $10 billion in market cap make up 24% of the total holdings value. On the other hand, small-cap stocks make up only 8.3% of the portfolio. The average market cap of the portfolio companies is close to $107 billion.

The complete list of Sphera Funds Management Ltd trades based on 13F SEC filings

These positions were updated on August 14th based on the fund’s latest 13F filing. Quickly find out what the most recently closed or increased positions are.

Security Shares Owned Value Allocation
BridgeBio Pharma Inc
55.31%
910,070
$23,052,073,000 3.76%
Sanofi
10.01%
449,515
$21,810,468,000 3.56%
Cytokinetics Inc
36.66%
384,924
$20,855,182,000 3.40%
Amazon.com Inc.
86.35%
101,432
$19,601,734,000 3.20%
Syndax Pharmaceuticals Inc
1.12%
822,047
$16,876,625,000 2.75%
Meta Platforms Inc
31.45%
33,439
$16,860,613,000 2.75%
Astrazeneca plc
No change
190,060
$14,822,779,000 2.42%
Perspective Therapeutics Inc
Closed
12,443,621
$14,807,909,000
Microsoft Corporation
19.53%
32,927
$14,716,723,000 2.40%
NICE Ltd
5.15%
81,461
$14,008,848,000 2.28%
Sarepta Therapeutics Inc
50.43%
83,659
$13,218,122,000 2.16%
Apple Inc
251.43%
61,500
$12,953,130,000 2.11%
Teva Pharmaceutical Inds Ltd
58.23%
789,416
$12,828,010,000 2.09%
Kura Oncology Inc
No change
610,826
$12,576,907,000 2.05%
Ultragenyx Pharmaceutical In
23.18%
293,832
$12,076,495,000 1.97%
Eli Lilly Co
7.05%
13,190
$11,941,962,000 1.95%
Praxis Precision Medicines I
60.00%
283,424
$11,722,417,000 1.91%
Celldex Therapeutics Inc.
11.65%
309,265
$11,445,898,000 1.87%
Novo-nordisk A S
6.02%
78,080
$11,145,139,000 1.82%
Biogen Inc
32.89%
47,412
$10,991,050,000 1.79%
Skye Bioscience Inc
Opened
1,298,312
$10,399,479,000 1.70%
Jasper Therapeutics Inc
10.10%
454,227
$10,310,953,000 1.68%
Johnson Johnson
12.53%
69,831
$10,206,499,000 1.66%
Asml Holding N V
Opened
9,901
$10,126,050,000 1.65%
Fusion Pharmaceuticals Inc.
Closed
449,041
$9,573,554,000
Merus N.V
1.14%
147,633
$8,735,445,000 1.42%
Salesforce Inc
Opened
33,600
$8,638,560,000 1.41%
Immatics N.v
9.76%
731,111
$8,495,510,000 1.39%
Perspective Therapeutics Inc
Opened
786,909
$7,845,483,000 1.28%
Pharvaris N V
2.64%
403,265
$7,581,382,000 1.24%
Merck Co Inc
42.47%
59,600
$7,378,480,000 1.20%
Rezolute Inc
71.36%
1,707,999
$7,344,396,000 1.20%
Cybin Inc
No change
25,581,395
$6,932,558,000 1.13%
Vigil Neuroscience Inc
2.21%
1,692,166
$6,768,664,000 1.10%
Ionis Pharmaceuticals Inc
Opened
140,238
$6,683,743,000 1.09%
Inozyme Pharma, Inc.
6.54%
1,462,724
$6,523,749,000 1.06%
Abbvie Inc
No change
38,000
$6,517,760,000 1.06%
Nova Ltd
Closed
35,106
$6,227,102,000
Palo Alto Networks Inc
Opened
18,000
$6,102,180,000 1.00%
Sentinelone Inc
48.48%
283,804
$5,974,074,000 0.97%
Tower Semiconductor Ltd.
16.70%
149,600
$5,880,776,000 0.96%
Applied Matls Inc
23.11%
24,604
$5,806,298,000 0.95%
Enphase Energy Inc
20.37%
56,792
$5,662,730,000 0.92%
Novartis AG
No change
50,000
$5,323,000,000 0.87%
Acadia Pharmaceuticals Inc
162.03%
327,539
$5,322,509,000 0.87%
Mineralys Therapeutics Inc
32.79%
442,752
$5,180,198,000 0.84%
Incyte Corp.
Closed
89,556
$5,102,005,000
4d Molecular Therapeutics In
49.56%
242,526
$5,090,621,000 0.83%
Micron Technology Inc.
Opened
37,000
$4,866,610,000 0.79%
Day One Biopharmaceuticals I
29.43%
347,627
$4,790,300,000 0.78%
Catalyst Pharmaceuticals Inc
No change
288,000
$4,461,120,000 0.73%
Rocket Pharmaceuticals Inc
12.63%
206,933
$4,455,267,000 0.73%
JFrog Ltd
47.46%
117,881
$4,426,432,000 0.72%
89bio Inc
2.07%
526,547
$4,217,641,000 0.69%
Outlook Therapeutics Inc
0.00%
571,428
$4,217,139,000 0.69%
Wix.com Ltd
52.39%
25,177
$4,004,905,000 0.65%
Lam Research Corp.
Opened
3,700
$3,939,945,000 0.64%
Savara Inc
Opened
962,687
$3,879,629,000 0.63%
GSK Plc
No change
100,000
$3,850,000,000 0.63%
Qualcomm, Inc.
25.50%
18,825
$3,749,564,000 0.61%
Eledon Pharmaceuticals, Inc.
Opened
1,297,021
$3,424,135,000 0.56%
Akero Therapeutics Inc
11.73%
141,620
$3,322,405,000 0.54%
Shl Telemedicine Ltd
No change
632,456
$3,223,438,000 0.53%
Applied Therapeutics, Inc.
8.92%
674,268
$3,148,832,000 0.51%
Intellia Therapeutics Inc
Opened
139,419
$3,120,197,000 0.51%
Broadcom Inc
1,834.07%
19,360
$3,108,306,000 0.51%
Analog Devices Inc.
Opened
13,000
$2,967,380,000 0.48%
PTC Therapeutics Inc
Opened
94,318
$2,884,244,000 0.47%
Solaredge Technologies Inc
Closed
40,175
$2,851,622,000
Vistagen Therapeutics Inc.
No change
808,550
$2,813,754,000 0.46%
Pliant Therapeutics, Inc.
No change
258,554
$2,779,456,000 0.45%
Alector, Inc.
8.93%
610,000
$2,769,400,000 0.45%
Enlight Renewable Energy Ltd
No change
169,280
$2,735,565,000 0.45%
Promis Neurosciences Inc
1.08%
1,814,213
$2,721,320,000 0.44%
KLA Corp.
Opened
3,300
$2,720,883,000 0.44%
SpringWorks Therapeutics, Inc.
No change
70,269
$2,647,033,000 0.43%
Disc Medicine Inc
18.73%
58,044
$2,616,043,000 0.43%
Cargo Therapeutics Inc
107.34%
155,506
$2,553,409,000 0.42%
Pfizer Inc.
No change
90,000
$2,518,200,000 0.41%
NVIDIA Corp
Opened
20,000
$2,470,800,000 0.40%
Global E Online Ltd
67.96%
66,884
$2,425,883,000 0.40%
Ventyx Biosciences Inc
2.01%
1,012,749
$2,339,450,000 0.38%
Taboola.com Ltd
43.97%
667,384
$2,295,801,000 0.37%
Larimar Therapeutics, Inc.
Opened
312,469
$2,265,400,000 0.37%
L3Harris Technologies Inc
Opened
10,000
$2,245,800,000 0.37%
ADC Therapeutics SA
Opened
685,547
$2,166,329,000 0.35%
Nutrien Ltd
13.99%
40,730
$2,073,564,000 0.34%
Elastic N.V
Closed
20,000
$2,004,800,000
Advanced Micro Devices Inc.
Closed
11,000
$1,985,390,000
Perion Network Ltd.
Opened
234,609
$1,958,985,000 0.32%
Alpine Immune Sciences Inc
Closed
44,841
$1,777,497,000
Kyverna Therapeutics Inc
Opened
236,029
$1,770,218,000 0.29%
Five9 Inc
Closed
27,500
$1,708,025,000
Alumis Inc
Opened
125,000
$1,662,500,000 0.27%
Eliem Therapeutics Inc
Opened
215,179
$1,529,923,000 0.25%
Werewolf Therapeutics Inc
No change
626,810
$1,529,416,000 0.25%
Astria Therapeutics Inc
44.31%
162,842
$1,481,862,000 0.24%
Vir Biotechnology Inc
Opened
162,051
$1,442,254,000 0.24%
Monte Rosa Therapeutics Inc
Opened
375,000
$1,402,500,000 0.23%
Marvell Technology Inc
Opened
20,000
$1,398,000,000 0.23%
Corbus Pharmaceuticals Hldgs
Closed
35,000
$1,373,400,000
Geron Corp.
Closed
384,356
$1,268,375,000
Upwork Inc
No change
117,000
$1,257,750,000 0.21%
Arrowhead Pharmaceuticals In
Opened
48,175
$1,252,068,000 0.20%
Compugen Ltd
3.90%
739,239
$1,241,922,000 0.20%
Kezar Life Sciences Inc
No change
2,051,676
$1,231,006,000 0.20%
Insmed Inc
Opened
16,589
$1,111,463,000 0.18%
Aprea Therapeutics, Inc.
No change
270,000
$1,098,900,000 0.18%
Taiwan Semiconductor Mfg Ltd
Opened
5,650
$982,027,000 0.16%
Elevation Oncology Inc
23.26%
330,000
$891,000,000 0.15%
Varonis Sys Inc
20.00%
16,000
$767,520,000 0.13%
Cartesian Therapeutics Inc
Opened
25,070
$677,141,000 0.11%
Argenx Se
Opened
1,556
$669,142,000 0.11%
Lava Therapeutics Nv
No change
367,582
$661,648,000 0.11%
Prime Medicine Inc
37.92%
127,424
$654,959,000 0.11%
Cartesian Therapeutics Inc
Closed
25,071
$488,889,000
Alto Neuroscience Inc
Closed
30,500
$468,175,000
ICL Group Ltd.
17.81%
107,238
$458,979,000 0.07%
Camtek Ltd
97.41%
1,940
$242,966,000 0.04%
Gossamer Bio, Inc.
78.37%
222,134
$200,121,000 0.03%
Arbe Robotics Ltd
No change
43,165
$82,445,000 0.01%
Amylyx Pharmaceuticals Inc
86.51%
36,050
$68,495,000 0.01%
No transactions found
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